NOTE:
This article is only for educational purpose. Consult with your physician about using a medicine with its off-label indication first before do anything!
Off-label indications are the usage of medicine out of its own listed indications as approved by local regulatory. Other name for off-label indication is "additional indication". This indication is usually based on empirical experience of some key opinion leaders in an institution or region. Off-label indications can sometimes emerge as on-label indication, has it passed phase IV trial and has it been approved by local or international regulatory.
Legally, the risk or casualty caused by the usage of a medicine for an off-label indication cannot be protected ethically (including that, this use of medicine sometimes not covered by health insurance!). So practically, usage of a medicine with its off-label indications should be conducted more carefully. Ask your physician about safety of the off-label indications before ask them to treat you by that medicine.