Medication Choice in Parkinson's Disease

Parkinson's disease (PD) is a neurological pathologic condition with the prevalence about 1 of every 100 individuals older than 55 years old in US alone. Main manifestations are commonly come from motoric system: resting tremor, rigidity of movement, bradykinesia, and postural instability (causes gait abnormality). Pathology of this disease is due to loss of dopaminergic neurons of the substansia nigra of the brain. This loss of dopaminergic neurons cause emergence of neurologic deficits which depend on dopaminergic system. Relatively, acetylcholine/dopamine ratio will rise and this cause more profound of tremor in patients.

Dementia (Alzheimer's Disease) Medicines: Choice Based on The Stage

Dementia is loss of cognitive ability and disturbance of mental function, due to certain process in brain. This condition often happens to elderly/aged person, but may also as a result of brain injury or other illness. There are many types of dementia, but the most common form of dementia is caused by Alzheimer's disease. Some other dementia types are vascular dementia, Parkinson's dementia, unspecified dementia, etc.

Several medicines have been developed and used as pharmacologic therapy to slow down dementia's progress.